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You can Contact Us to request technical support for this software or to report any issues you encounter when using it. We accept several types of messages from our users, these include bug reports, feature requests, and inquiries regarding the workings of the software. Contacting us is quick and easy, just fill out the following form and we will respond as soon as possible. and who knows? Perhaps human follicles can become “stem” cells, a notion recently championed by S. James Potten in the journal Human Reproduction.
But what lies at the heart of follicle development? Well, there’s still an answer to that question, even if the answer is not quite as simple as researchers thought just a few years ago. Recent work by Sheena Salz-Passerini and many others has unraveled the complex signaling network involved in both animal and human follicle development. This network includes, for instance, a receptor for BMP proteins called ALK2, which is a key gene that turns on a cascade of other genes including stem cells genes that help follicle cells grow and become eggs.
And we’re still learning more, including which of these genes and signaling molecules are important in both the adult and the embryonic follicles, as well as how these molecular changes impact follicle development from the earliest stages to just before ovulation.
So if we manage to translate what we learn about follicle development from the ovaries to the testes, then human testes may hold the answer to many of our own follicle problems. If anything, it would be nice to be able to know how the testes develop in more detail than we know right now — could it be that they start out similar to ovarian follicles until they turn into something very different?
Finally, if you are one of my readers in the United States, you may have noticed that I have been away from my blog for several months. This is because I have been working on a book called “Beyond Eggs and Sperm: From Human Reproduction to Regenerative Biology,” which should be ready for the printer any day now.
My co-authors on the book, Jeff Tatum and Michael J. Klagsbrun, are both Ph.D. candidates in regenerative medicine. Jeff, like me, also has a Ph.D. in reproductive biology from the University of Iowa. Michael’s parents founded the Jaffe-Tatum Institute https://ebimarketing.com/wp-content/uploads/2022/06/gysnan.pdf
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