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3ds max 2017 final edition 64 bit Keygen Autodesk ::: ::: DOWNLOAD Entering an. Full Version Autodesk 3DS Max 2017 Free Download ISO Bit With X. Autodesk-AutoCAD-Civil-3D-2018-x64-ISO-Keygen-SadeemPC-download-.Oral anticoagulation in the elderly: the influence of drug treatment on age-related changes in surrogate outcomes of atrial fibrillation.
Atrial fibrillation (AF) is a common arrhythmia in the elderly, yet it remains under-managed due to age-related comorbidities, polypharmacy and patient preferences. Oral anticoagulation (OAC) is the recommended treatment for AF, but it is unclear whether elderly people are able to tolerate the treatment and whether this influences the effects on comorbidities. We conducted a systematic literature search for randomized controlled trials comparing OAC with placebo in the elderly. Our primary outcomes were haemostatic efficacy, mortality and morbidity. Secondary outcomes were stroke, bleeding, quality of life (QoL), healthcare costs and health care resource utilization. Random effects meta-analyses were conducted using adjusted data from trials with comparable methodological quality. Included trials were published between 1966 and 2008. Six trials were identified, with a total of 4814 patients (age > or = 65 years). All trials had at least one co-treatment and were assessed to be of high quality. No significant difference was observed between OAC and placebo in all-cause mortality (relative risk [RR] 0.99, 95% confidence interval [CI] 0.87-1.13) or total major adverse cardiovascular events (MACE; including non-fatal myocardial infarction, non-fatal stroke or cardiovascular death; RR 0.92, 95% CI 0.81-1.05). Bleeding, particularly intracranial bleeding, was more frequent with
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